This book contains 71 original, scientific articles that address state-of-the-art researchrelatedto scale space and variationalmethods for image processing and computer vision. Topics covered in the book range from mathematical analysis of both established and new models, fast numerical methods, image analysis, segmentation, registration, surface and shape construction and processing, to real applications in medical imaging and computer vision. The ideas of scale space and variational methods related to partial differentiale quations are central concepts. The papers reffect the newest developments in these fields and also point to the latest literature. All the papers were submitted to the Second International Conference on Scale Space and Variational Methods in Computer Vision, which took place in Voss, Norway, during June 1–5, 2009. The papers underwent a peer review process similar to that of high-level journals in the field. We thank the authors, the Scientific Committee, the Program Committee and the reviewers for their hard work and helpful collaboration. Their contribution has been crucial for the efficient processing of this book, and for the success of the conference.